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Citation: Kouas S, Zoukar O, Issa R, Ikridih K, Mahdhi S, Haddad A. Sclerosing stromal ovarian tumor.Jr.med.res.2020;3(3): 24-25. Kouas et al © All
rights are reserved. https://doi.org/10.32512/jmr.3.3.2020/24.25
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Images in clinical practice
Sclerosing stromal ovarian tumor.
Figure 1: solid well encapsulated ovarian mass with no focal hemorrhage or necrosis and yellow cut surface
Figure 2: pseudo-lobular aspect of cells proliferation separated by edematous, myxoid hypocellular areas
Kouas Sofiane
1,3*
, Zoukar Olfa
2,3
, Issa Rahma
1,3
, Ikridih Khouloud
1,3
, Mahdhi Sameh
1,3
, Haddad Anis
2,3
.
1: Department of Gynecology and Obstetrics
Tahar Sfar Hospital Mahdia, Tunisia
2: Department of Gynecology and Obstetrics
El Omrane Hospital Monastir, Tunisia
3: College of medicine Monastir, Tunisia
* Corresponding author
Correspondence to:
sofianekouas@gmail.com
Publication Data:
Submitted: August 28,2020
Accepted: October 3,2020
Online: November 30,2020
This article was subject to full peer-review.
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Sclerosing stromal ovarian tumor.
Citation: Kouas S, Zoukar O, Issa R, Ikridih K, Mahdhi S, Haddad A. Sclerosing stromal ovarian tumor.Jr.med.res.2020;3(3): 24-25. Omrani et al © All
rights are reserved. Kouas et al © All rights are reserved.
Submit your manuscript: www.jmedicalresearch.com
25
Observation
An 18-year-old female presented with left-sided recurrent lower abdominal pain. The physical examination was
unremarkable. Preoperative investigations confirmed a solid mass measuring 5x6 cm. Laboratory investigations
including tumor markers were normal. The patient underwent unilateral salpingo-oophorectomy with uneventful
postoperative course. The histopathologic gross examination revealed yellowish ovarian tumor of 53 grams with no
focal hemorrhage or necrosis (figure1). Microscopic examination revealed heterogeneous cell proliferation separated
by edematous, myxoid, and fibrous hypocellular areas (Figure 2). The tumor was well circumscribed with pseudo-
lobular aspect. The immunostaining showed moderate positivity to Calretinin, Inhibin and smooth muscle actin.
However, the tumor was negative for Pancytokeratin.
Sex cord-stromal tumors are rare ovarian neoplasms. Described first in 1973, sclerosing stromal tumor (SST) is a
subtype that accounts for less than 6% of all ovarian tumors[1]. This entity with specific immunohistochemical
characteristics is mostly diagnosed in young active females and usually non- secreting [2]. The clinical and radiological
features are nonspecific. The diagnosis is always made by the pathological examination of resected tumor specimen
[3].
Conflict of Interest: None
References
[1] Young RH. Ovarian Sex Cord-Stromal Tumors: Reflections on a 40-Year Experience with a fascinating group of tumors, including comments on the seminal
observations of Robert E. Scully, MD. Arch Pathol Lab Med. 2018;142:1459-84.
[2] Bairwa S, Satarkar RN, Kalhan S, Garg S, Sangwaiya A, Singh P. Sclerosing Stromal Tumor: A Rare Ovarian Neoplasm. Iran J Pathol. 2017 ;12:402-05.
[3] Nguyen M, Soumit N, Waheed A, Sees J, Azhar E. A Rare Case of Sclerosing Stromal Tumor of the Ovary Presenting in Pregnancy: A Diagnostic Dilemma on
Presentation. Case Rep Obstet Gynecol. 2019;2019:3927971.
